Sotirios G Doukas Selected Research

3- (4- methylphenylsulfonyl)- 2- propenenitrile

9/2020	The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model.
5/2019	Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells.
1/2018	NF-κB inhibition reverses acidic bile-induced miR-21, miR-155, miR-192, miR-34a, miR-375 and miR-451a deregulations in human hypopharyngeal cells.
1/2018	Curcumin prevents the bile reflux-induced NF-κB-related mRNA oncogenic phenotype, in human hypopharyngeal cells.
1/2018	In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile-Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa.

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Sotirios G Doukas Research Topics

Disease

10	Neoplasms (Cancer) 09/2021 - 01/2013
4	Bile Reflux 01/2022 - 01/2018
4	Hypopharyngeal Neoplasms 01/2022 - 01/2018
3	Squamous Cell Carcinoma of Head and Neck 01/2022 - 10/2019
3	Carcinogenesis 01/2022 - 01/2013
2	COVID-19 04/2022 - 09/2021
2	Carcinoma (Carcinomatosis) 01/2022 - 01/2013
2	Head and Neck Neoplasms (Head and Neck Cancer) 11/2021 - 01/2018
2	Squamous Cell Neoplasms (Squamous Cell Cancer) 11/2021 - 01/2020
2	Gastroesophageal Reflux (GERD) 02/2021 - 01/2020
1	Transverse Myelitis (Necrotizing Myelitis) 04/2022
1	Hypoxia (Hypoxemia) 04/2022
1	Urinary Retention 04/2022
1	Pericardial Effusion 04/2022
1	Bradycardia 04/2022
1	Hypotension (Low Blood Pressure) 04/2022
1	Pulmonary Embolism 09/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 09/2021
1	Renal Cell Carcinoma (Grawitz Tumor) 07/2021
1	Dyspnea (Shortness of Breath) 07/2021
1	Weight Loss (Weight Reduction) 07/2021
1	Membranous Glomerulonephritis (Membranous Nephropathy) 06/2021
1	Disease Progression 06/2021
1	Amyloidosis 03/2020
1	Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal) 10/2013
1	Turcot syndrome 10/2013
1	Polyps 10/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2013
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2013
1	Adenocarcinoma 01/2013
1	Adenocarcinoma of Lung 01/2013
1	Lung Neoplasms (Lung Cancer) 01/2013
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2013

Drug/Important Bio-Agent (IBA)

8	Messenger RNA (mRNA)IBA 11/2021 - 01/2013
5	3- (4- methylphenylsulfonyl)- 2- propenenitrileIBA 09/2020 - 01/2018
4	MicroRNAs (MicroRNA)IBA 11/2021 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 03/2020 - 01/2013
3	Interleukin-6 (Interleukin 6)IBA 10/2019 - 01/2018
2	SmokeIBA 01/2022 - 01/2020
2	AntacidsIBA 02/2021 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 04/2020 - 01/2020
2	CurcuminIBA 01/2020 - 01/2018
2	LuciferasesIBA 05/2019 - 01/2018
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 04/2022
1	Methylprednisolone FDA LinkGeneric 04/2022
1	Peroxidase (Myeloperoxidase)IBA 04/2022
1	Myelin-Oligodendrocyte GlycoproteinIBA 04/2022
1	Gabapentin (Neurontin)FDA LinkGeneric 04/2022
1	ElectrolytesIBA 04/2022
1	Glucose (Dextrose)FDA LinkGeneric 04/2022
1	NitrosaminesIBA 01/2022
1	trans-sodium crocetinate (crocetin)IBA 01/2022
1	Deoxycholic Acid (Sodium Deoxycholate)IBA 01/2022
1	fibrin fragment D (D-dimer)IBA 09/2021
1	Hormones (Hormone)IBA 07/2021
1	cetrorelix (Cetrotide)FDA Link 07/2021
1	follitropin alfa (Gonal F)FDA Link 07/2021
1	Leuprolide (Lupron)FDA LinkGeneric 07/2021
1	AntibodiesIBA 06/2021
1	Phospholipase A2 ReceptorsIBA 06/2021
1	AntigensIBA 03/2020
1	CarcinogensIBA 01/2020
1	nitrosamine 4- (methylnitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 01/2020
1	Bile Acids and Salts (Bile Acids)IBA 01/2020
1	Melanins (Melanin)IBA 10/2013
1	P-2 (P 2)IBA 01/2013

Therapy/Procedure

4	Therapeutics 01/2022 - 01/2020
1	Injections 07/2021
1	Adjuvant Chemotherapy 01/2013